Br J Haematol. 2025 Dec 23. doi: 10.1111/bjh.70283. Online ahead of print.
ABSTRACT
This is a new British Society of Haematology (BSH) guideline which focuses on the management of hepatitis B and C (HBV and HCV) infection affecting people with bleeding disorders (PwBD), including those who cleared the infection many years previously. It is based on the European Association for the Study of the Liver (EASL) guidance and is a succinct practical guide for haematologists to support joint care with hepatology. It is compatible with the joint international guidance from the European Association for Haemophilia and Allied Disorders, European Haemophilia Consortium, International Society on Thrombosis and Haemostasis (ISTH) and World Federation of Hemophilia 2024. However, it provides more specific guidance on investigations for fibrosis/cirrhosis and thresholds for onwards referral to hepatology in those who cleared HCV historically (either through spontaneous clearance or following effective treatment). The aim of this guideline is to improve the management of this group of patients nationally as well as potentially supporting the management of this group of patients internationally. It also contributes to the delivery of recommendations made by the UK Infected Blood Inquiry 2024.
PMID:41431438 | DOI:10.1111/bjh.70283