JACC Case Rep. 2026 Mar 17:107368. doi: 10.1016/j.jaccas.2026.107368. Online ahead of print.ABSTRACTBACKGROUND: Pregnancy-associated pulmonary embolism (PE) represents a rare but life-threatening condition, with limited evidence to guide management. Reperfusion therapy must be carefully balanced aga
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2026 Feb;34(1):272-278. doi: 10.19746/j.cnki.issn.1009-2137.2026.01.040.ABSTRACTOBJECTIVE: To investigate the effect of ellagic acid on the growth and platelet-producing function of megakaryocytes after X-ray irradiation, in order to clarify the therapeutic effect
JCI Insight. 2026 Mar 17:e203211. doi: 10.1172/jci.insight.203211. Online ahead of print.ABSTRACTGlucagon-like peptide-1 (GLP-1) and glucose-induced insulinotropic polypeptide (GIP) receptor agonists have revolutionized obesity therapy but causes for obesity-associated dysregulation of endogenous in
No abstractThromb J. 2026 Mar 16. doi: 10.1186/s12959-026-00852-x. Online ahead of print.NO ABSTRACTPMID:41840609 | DOI:10.1186/s12959-026-00852-x
J Thromb Haemost. 2026 Mar 14:S1538-7836(26)00190-X. doi: 10.1016/j.jtha.2026.03.005. Online ahead of print.ABSTRACTBACKGROUND: D-dimer testing is widely integrated into diagnostic algorithms for venous thromboembolism (VTE). However, the lack of standardization across D-dimer assays and reporting m
No abstractThromb Haemost. 2026 Mar 16. doi: 10.1055/a-2827-2069. Online ahead of print.NO ABSTRACTPMID:41839219 | DOI:10.1055/a-2827-2069
Int J Surg Case Rep. 2026 Feb 19;138(3):425-429. doi: 10.1097/RC9.0000000000000112. eCollection 2026 Mar.ABSTRACTINTRODUCTION AND IMPORTANCE: Heparin-induced thrombocytopenia (HIT) is a severe adverse immune mediated reaction to heparin therapy, particularly relevant in vascular surgery due to its p
J Thromb Haemost. 2026 Mar 13:S1538-7836(26)00186-8. doi: 10.1016/j.jtha.2026.03.001. Online ahead of print.ABSTRACTINTRODUCTION: Long-term follow up of children with venous thromboembolism (VTE) is necessary to diagnose post-thrombotic sequelae, though current practice is not standardized. The ASTR
Lancet. 2026 Mar 12:S0140-6736(26)00150-9. doi: 10.1016/S0140-6736(26)00150-9. Online ahead of print.ABSTRACTHereditary haemolytic anaemias represent the most prevalent group of genetic disorders worldwide and have a substantial impact on global health. Current treatments are few and primarily suppo
Ann Vasc Surg. 2026 Mar 12:S0890-5096(26)00130-5. doi: 10.1016/j.avsg.2026.02.036. Online ahead of print.ABSTRACTINTRODUCTION: Percutaneous endovascular aortic repair (pEVAR) has become the gold standard in the treatment of aortic aneurysms. Vascular puncture site complications can have severe impli
Nutrients. 2026 Feb 26;18(5):763. doi: 10.3390/nu18050763.ABSTRACTInsulin resistance (IR) promotes a prothrombotic milieu by enhancing platelet hyperactivity, oxidative stress, and endothelial dysfunction, driving both microvascular and macrovascular complications in type 2 diabetes. Our review synt
Int J Mol Sci. 2026 Mar 9;27(5):2515. doi: 10.3390/ijms27052515.ABSTRACTCancer-associated thrombosis (CAT) is a major cause of morbidity and mortality in oncology, arising from complex interactions between tumor biology, host factors, and anticancer therapies. Growing evidence indicates that biologi
Int J Mol Sci. 2026 Mar 2;27(5):2330. doi: 10.3390/ijms27052330.ABSTRACTNKAP (NF-kappa-B-activating protein) is a ubiquitously expressed nuclear protein involved in multiple biological processes. Males with missense NKAP mutations have been reported to present with marfanoid features and behavioral
Int J Mol Sci. 2026 Feb 28;27(5):2282. doi: 10.3390/ijms27052282.ABSTRACTProtein C (PC) and its activated form, activated protein C (APC), are well-established regulators of coagulation and cytoprotection. While their systemic functions are extensively characterized, their physiological roles in the
Int J Mol Sci. 2026 Feb 25;27(5):2164. doi: 10.3390/ijms27052164.ABSTRACTInvestigation of dialyzer thrombogenicity is a critical step during the development of a new dialyzer. Novel dialyzer membranes aim to reduce the inherent thrombogenic potential of artificial surfaces by, e.g., increasing membr
Diagnostics (Basel). 2026 Mar 8;16(5):800. doi: 10.3390/diagnostics16050800.ABSTRACTPortal vein thrombosis (PVT) refers specifically to the presence of a thrombus within the main portal vein trunk or its intrahepatic branches. In contrast, portal vein occlusion encompasses a broader spectrum of cond
J Clin Med. 2026 Mar 7;15(5):2036. doi: 10.3390/jcm15052036.ABSTRACTThe development of thrombocytopenia is common in cirrhosis. Further complex alterations in haemostasis also occur, resulting in a rebalanced state that predisposes patients to both thromboembolic and bleeding complications. Guidance
J Clin Med. 2026 Feb 26;15(5):1759. doi: 10.3390/jcm15051759.ABSTRACTBackground: Blood transfusion practices have evolved significantly in order to enhance patient care. The optimal strategies for administering red blood cell (RBC) transfusions is becoming rather clear; however, a comprehensive unde
J Clin Med. 2026 Feb 24;15(5):1696. doi: 10.3390/jcm15051696.ABSTRACTBackground: Adequate analgesia is essential for enhanced recovery following major abdominal and thoracic surgery. Intravenous methadone has emerged as an alternative analgesic modality to traditional epidural analgesia. This study
Hamostaseologie. 2026 Mar 13. doi: 10.1055/a-2791-8607. Online ahead of print.ABSTRACTPostviral antiplatelet factor 4 (PF4) immunothrombosis is an emerging pediatric entity characterized by thrombocytopenia, thrombosis, and markedly elevated D-dimer levels and anti-PF4 antibodies. It shares immunopa
Lancet Haematol. 2026 Mar 10:S2352-3026(26)00009-8. doi: 10.1016/S2352-3026(26)00009-8. Online ahead of print.ABSTRACTRebalancing agents represent a novel therapeutic class in haemophilia, designed to restore the deficient thrombin generation that underlies bleeding. Unlike factor replacement or fac
Lancet Haematol. 2026 Mar 10:S2352-3026(26)00008-6. doi: 10.1016/S2352-3026(26)00008-6. Online ahead of print.ABSTRACTHaemophilia care has progressed through successive therapeutic revolutions, from plasma-derived and recombinant factor replacement to extended half-life products and non-factor thera
Blood. 2026 Mar 13:blood.2025031420. doi: 10.1182/blood.2025031420. Online ahead of print.ABSTRACTMice lacking Tissue Factor Pathway Inhibitor (Tfpi-/-) succumb to embryonic lethality from excess thrombin production and associated cerebrovascular defects called glomeruloid bodies. A transgene produc
Pediatr Crit Care Med. 2026 Mar 13. doi: 10.1097/PCC.0000000000003938. Online ahead of print.ABSTRACTOBJECTIVES: The parenteral anticoagulant bivalirudin has favorable safety and efficacy outcomes compared with unfractionated heparin (UFH) in pediatric patients requiring extracorporeal membrane oxyg
