Intern Med. 2026 Mar 17. doi: 10.2169/internalmedicine.6800-25. Online ahead of print.
ABSTRACT
Nontyphoidal Salmonella (NTS) commonly causes acute gastroenteritis. It can also lead to invasive infections such as osteomyelitis. However, these are rare occurrences in healthy individuals. A healthy Japanese man in his 30s presented with right leg pain and a cutaneous fistula that persisted for four months. NTS was identified in the bone culture. The patient was treated with ceftriaxone and de-escalated to ampicillin, followed by oral amoxicillin. This case demonstrates that chronic osteomyelitis caused by NTS can present as a cutaneous fistula. Furthermore, it underscores the importance of obtaining a bone culture to identify the causative organism and ensure an accurate diagnosis.
PMID:41850832 | DOI:10.2169/internalmedicine.6800-25