BMC Surg. 2025 Dec 26. doi: 10.1186/s12893-025-03447-x. Online ahead of print.ABSTRACTBACKGROUND: Abdominal ectopic bronchogenic cysts (EBCs) are rare congenital malformations that are frequently misdiagnosed preoperatively due to their nonspecific and often asymptomatic presentation. This study aim
Front Med (Lausanne). 2025 Dec 9;12:1702870. doi: 10.3389/fmed.2025.1702870. eCollection 2025.ABSTRACTAlveolar soft part sarcoma (ASPS) is a rare malignant soft tissue neoplasm characterized by distinctive histological features, indolent growth patterns and a propensity for metastasis. Recent advanc
Alzheimers Dement. 2025 Dec;21 Suppl 2(Suppl 2):e099562. doi: 10.1002/alz70856_099562.ABSTRACTBACKGROUND: Alzheimer's disease (AD) and its precursor, mild cognitive impairment (MCI), present significant challenges due to heterogeneous progression and treatment responses. Identifying subgroups of pat
J Pers Med. 2025 Dec 1;15(12):586. doi: 10.3390/jpm15120586.ABSTRACTBackground: Secretan's syndrome is a rare and under-recognized condition characterized by chronic, indurated, non-pitting edema of the dorsal hand with thumb sparing. Twelve studies reporting 17 patients have been published worldwid
Front Endocrinol (Lausanne). 2025 Dec 8;16:1706780. doi: 10.3389/fendo.2025.1706780. eCollection 2025.ABSTRACTINTRODUCTION: Obesity is a pressing global endocrine disorder that disrupts hormonal axes and elevates the risk of type 2 diabetes, cardiovascular disease, and metabolic conditions. Early an
Alzheimers Dement. 2025 Dec;21 Suppl 9(Suppl 9):e110678. doi: 10.1002/alz70863_110678.ABSTRACTBACKGROUND: Primary care visits offer an important opportunity for early detection of cognitive impairment (CI) in adults over age 65, yet less than half of patients with any CI are identified in primary ca
Clin Rheumatol. 2025 Dec 23. doi: 10.1007/s10067-025-07880-4. Online ahead of print.ABSTRACTOBJECTIVES: Systemic lupus erythematosus (SLE) is a life-threatening autoimmune disorder causing multi-organ damage. Current diagnostic methods are hindered by inadequate sensitivity and specificity of conven
Head Neck Pathol. 2025 Dec 22;20(1):2. doi: 10.1007/s12105-025-01868-x.ABSTRACTPURPOSE: To evaluate the diagnostic yield and clinical impact of a comprehensive RNA-based sequencing panel ("SalvGlandDx version 2") in the work-up of salivary gland tumors.METHODS: Between 2021 and 2025, 118 salivary gl
Oncol Res. 2025 Nov 27;33(12):3701-3730. doi: 10.32604/or.2025.068432. eCollection 2025.ABSTRACTOvarian endometrioid carcinoma (OEC) accounts for ~10% of epithelial ovarian cancers and displays broad morphologic diversity that complicates diagnosis and grading. Recent data show that the endometrial
J Nurs Manag. 2025 Dec 16;2025:8038903. doi: 10.1155/jonm/8038903. eCollection 2025.ABSTRACTBACKGROUND: The noninvasive diagnosis of pancreatic lesions is a critical clinical challenge. This study aims to create machine learning (ML) radiomic models for differentiating pancreatic lesions and an inte
Sci Rep. 2025 Dec 19;15(1):44199. doi: 10.1038/s41598-025-27942-6.ABSTRACTThe importance of microbiota-associated metabolites in pancreatic ductal adenocarcinoma (PDAC) tumorigenesis highlights the need to investigate the microbiota and metabolome along the normal-adjacent-carcinoma sequence to expl
Neuroradiol J. 2025 Dec 19:19714009251407172. doi: 10.1177/19714009251407172. Online ahead of print.ABSTRACTLeptomeningeal diseases represent a diverse group of pathological conditions affecting the pia and arachnoid mater, encompassing a wide spectrum of infective-inflammatory, neoplastic, and vasc
Cureus. 2025 Nov 16;17(11):e97006. doi: 10.7759/cureus.97006. eCollection 2025 Nov.ABSTRACTOBJECTIVE: Malignant lymphoma (ML), a lymphocyte-derived malignancy, is classified into Hodgkin lymphoma and non-Hodgkin lymphoma (NHL). In the oral cavity, NHL is the predominant type. However, diagnosing ora
J Neurol. 2025 Dec 17;273(1):29. doi: 10.1007/s00415-025-13539-6.ABSTRACTProgressive supranuclear palsy (PSP) is a rare and debilitating four-repeat (4R) tauopathy, characterized by motor dysfunction, cognitive decline, and oculomotor abnormalities, yet it lacks reliable biomarkers for early diagnos
Radiol Case Rep. 2025 Nov 28;21(2):824-826. doi: 10.1016/j.radcr.2025.10.085. eCollection 2026 Feb.ABSTRACTPeritoneal tuberculosis (TB) can closely mimic peritoneal carcinomatosis on cross-sectional imaging, creating a major diagnostic dilemma in oncologic patients. We describe a 49-year-old man wit
Beijing Da Xue Xue Bao Yi Xue Ban. 2025 Dec 18;57(6):1188-1192. doi: 10.19723/j.issn.1671-167X.2025.06.026.ABSTRACTThis article presents a comprehensive case analysis of a young female patient with systemic lupus erythematosus (SLE) who developed neuropsychiatric symptoms during prolonged immunosupp
Med Int (Lond). 2025 Dec 1;6(1):4. doi: 10.3892/mi.2025.288. eCollection 2026 Jan-Feb.ABSTRACTCreutzfeldt-Jakob Disease (CJD) is a rare, rapidly progressive and fatal prion encephalopathy characterized by cognitive deterioration, motor dysfunction and myoclonus. The present study describes the case
World J Gastroenterol. 2025 Dec 7;31(45):112436. doi: 10.3748/wjg.v31.i45.112436.ABSTRACTThe management of biliary strictures is challenging both diagnostically and therapeutically, requiring a combination of advanced endoscopic techniques. Endoscopic retrograde cholangiopancreatography (ERCP) remai
J Clin Med. 2025 Nov 28;14(23):8458. doi: 10.3390/jcm14238458.ABSTRACTTechnetium-99m bone scintigraphy has revolutionized the non-invasive diagnosis of transthyretin cardiac amyloidosis (ATTR-CM) and markedly increased disease recognition. Although this technique should ideally be applied in patient
J Clin Med. 2025 Nov 25;14(23):8370. doi: 10.3390/jcm14238370.ABSTRACTBackground/Objectives: Wells' syndrome (WS) is an uncommon cutaneous disease with unknown etiology. Itchy bullous lesions and erythematous plaques characterize the bullous WS (BWS), a rare subtype of the syndrome. We describe the
JMIR Form Res. 2025 Dec 10;9:e79208. doi: 10.2196/79208.ABSTRACTBACKGROUND: Early cancer detection is crucial, but recognizing the significance of associated symptoms such as unintended weight loss in primary care remains challenging. Clinical decision support systems (CDSSs) can aid cancer detectio
Clin Exp Dermatol. 2025 Dec 10:llaf522. doi: 10.1093/ced/llaf522. Online ahead of print.ABSTRACTPediculosis capitis, caused by Pediculus humanus capitis, is a common ectoparasitic infestation primarily affecting school-aged children worldwide. It is transmitted through direct head-to-head contact an
Medicine (Baltimore). 2025 Dec 5;104(49):e46056. doi: 10.1097/MD.0000000000046056.ABSTRACTThis study developed an magnetic resonance imaging (MRI)-based multiclass model for the preoperative differentiation of primary liver cancer (PLC) subtypes by integrating radiomic and clinicoradiological featur
BMC Cardiovasc Disord. 2025 Dec 9;25(1):861. doi: 10.1186/s12872-025-05162-0.ABSTRACTBACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CA) results from extracellular misfolded transthyretin deposition. Technetium-99 m pyrophosphate (99mTc-PYP) scintigraphy serves as the noninvasive diagnostic g
